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medical-notes/content/Fysiologi/Canvas/Del I/Block 1 - Nervcellsfysiologi/Brain development VT22.md
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Brain development .pdf

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Page 1

Brain Development Block 2 Nervcellsfysiologi Eric Hanse Läroböcker: Bear kap:23-25 Purves kap:22-25


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Overview 10 w 20 w 30 w Birth 1 y Puberty Neurons Synapses Glia Proliferation Differentiation Migration Neurite outgrowth Synaptogenesis Apoptosis Synaptic reorganization Myelination


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Normal and pathological development of synapses Forrest, Parnell and Penzes 2018 Nat Rev Neurosci 19:215-234


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AMPA silent synapses Hanse, Seth & Riebe 2013 Nat Rev Neurosci 14:839


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Maturation of Glu synapses Hanse, Seth & Riebe 2013 Nat Rev Neurosci 14:839


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GABA is depolarasing during the early brain development Ben-Ari 2002 Nat Rev Neurosci 3:728


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Fig. 2 Corticogenesis and relationship with spontaneous activity patterns. Zoltán Molnár et al. Science 2020;370:eabb2153 Spontaneous neural activity drives the early developement of the brain