# Brain development .pdf **OCR Transcript** - Pages: 7 - OCR Engine: pymupdf - Quality Score: 1.00 --- ## Page 1 Brain Development Block 2 Nervcellsfysiologi Eric Hanse Läroböcker: Bear kap:23-25 Purves kap:22-25 --- ## Page 2 Overview 10 w 20 w 30 w Birth 1 y Puberty Neurons Synapses Glia Proliferation Differentiation Migration Neurite outgrowth Synaptogenesis Apoptosis Synaptic reorganization Myelination --- ## Page 3 Normal and pathological development of synapses Forrest, Parnell and Penzes 2018 Nat Rev Neurosci 19:215-234 --- ## Page 4 AMPA silent synapses Hanse, Seth & Riebe 2013 Nat Rev Neurosci 14:839 --- ## Page 5 Maturation of Glu synapses Hanse, Seth & Riebe 2013 Nat Rev Neurosci 14:839 --- ## Page 6 GABA is depolarasing during the early brain development Ben-Ari 2002 Nat Rev Neurosci 3:728 --- ## Page 7 Fig. 2 Corticogenesis and relationship with spontaneous activity patterns. Zoltán Molnár et al. Science 2020;370:eabb2153 Spontaneous neural activity drives the early developement of the brain ---