Johan Dahlin
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27 lines
787 B
Markdown
27 lines
787 B
Markdown
---
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date: 2025-02-01
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tags:
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- biokemi
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- provfråga
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- hemoglobin
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---
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**Uppgift**
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A) Name two allosteric regulators of oxygen binding to hemoglobin.
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B) Explain an outcome for each regulator.
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(Max 100 words.) Please answer this question in English. (4p)
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**Answer**
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```spoiler-block
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a) O₂ and CO₂
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b)
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O₂:
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Hemoglobin has four subunits that bind to O₂ through cooperativity, meaning that if one subunit binds to an O₂, the other subunits' affinity for O₂ will increase, leading to all subunits binding to O₂. When O₂ binds, the state goes from T-state (deoxy; tense) to R-state (oxy; relaxed).
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CO₂:
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When CO₂ binds to hemoglobin, the hemoglobin's affinity to oxygen decreases, leading to a stabilization of the T-state instead.
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```
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Totalpoäng: 4
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