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Johan Dahlin
2025-11-27 13:29:21 +01:00
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content/Biokemi/Cellulära processer/Translation/Stoff.md
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@@ -56,7 +56,14 @@ IF1 and IF3 bind the 30S subunit to prevent premature binding to the 50S subunit
IF2(GTP) initiator- fMet-tRNA fMet complex binds with mRNA and the 30S subunit to form the 30S initiation complex
70S initiation complex formation is the rate-limiting step in protein biosynthesis
Antibiotic Streptomycin Binds to 30S ribosomal subunit and interferes with the binding of fMet-tRNA fMet (Specific to bacteria)
Elongation factors deliver aminoacyl-tRNAs to the ribosome
Antibiotic Tetracycline Binds to 30S ribosomal subunit and inhibits the binding of aminoacyl-tRNAs (bacteria) Elongation
Elongation – peptidyl transferase catalyzes peptide-bond formation
peptidyl transferase center = a site on the 50S subunit that catalyzes the thermodynamically spontaneous formation of the peptide bond
image av tRNA + beskrivningar för anticodon, CCA, N-term, C-term
```
Stop 28:55 av https://www.youtube.com/watch?v=gjjp-NUaCXE
Stop 28:55 av https://www.youtube.com/watch?v=gjjp-NUaCXE
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