---
date: 2025-02-01
tags:
  - biokemi
  - provfråga
  - hemoglobin
---

**Uppgift**  
A) Name two allosteric regulators of oxygen binding to hemoglobin.  
B) Explain an outcome for each regulator.  
(Max 100 words.) Please answer this question in English. (4p)

**Answer**
```spoiler-block

a) O₂ and CO₂  
b)  
O₂:  
Hemoglobin has four subunits that bind to O₂ through cooperativity, meaning that if one subunit binds to an O₂, the other subunits' affinity for O₂ will increase, leading to all subunits binding to O₂. When O₂ binds, the state goes from T-state (deoxy; tense) to R-state (oxy; relaxed).  

CO₂:  
When CO₂ binds to hemoglobin, the hemoglobin's affinity to oxygen decreases, leading to a stabilization of the T-state instead.  

```
Totalpoäng: 4