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@@ -1,4 +1,4 @@
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The aim of the study was to investigate whether normal aging lea. ds to blood cells being produced from fewer cell clones. This was examined by comparing which X chromosome the cells were using between different age groups and between neutrophils and T cells.
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The aim of the study was to investigate whether normal aging leads to blood cells being produced from fewer cell clones. This was examined by comparing which X chromosome the cells were using between different age groups and between neutrophils and T cells.
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In other words, they studied human hematopoiesis across age by analyzing purified blood cell lineages from the subjects.
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-----
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@@ -31,7 +31,6 @@ Conclusion: Newborns mostly show balanced use of the two X chromosomes
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</small>
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---
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### > 75 years neutrophils
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![[image-184.png|145x158]]
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@@ -40,3 +39,11 @@ Conclusion: Newborns mostly show balanced use of the two X chromosomes
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- X and Y axis is the same as in previous graph
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Conclusion: Elderly neutrophils frequently show strongly uneven X chromosome usage.
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</small>
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----
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### Questions
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- What was the main question the authors wanted to answer?
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- Why did they choose this specific method instead of another one?
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- What does this figure show in one sentence?
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- What is the main conclusion from your article?
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- What would be the biggest limitation of this study?
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