vault backup: 2026-01-16 11:47:33

content/.obsidian/plugins/image-converter/image-converter-image-alignments.json

@@ -1 +1,16 @@
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+  "Vetenskaplig artikel/Methods & Main Results.md": {
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+      "position": "center",
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content/Vetenskaplig artikel/Methods & Main Results.md

@@ -1,12 +1,12 @@
-The aim of the study was to investigate whether normal aging leads to blood cells being produced from fewer cell clones. This was examined by comparing which X chromosome the cells were using between different age groups and between neutrophils and T cells.
+The aim of the study was to investigate whether normal aging lea. ds to blood cells being produced from fewer cell clones. This was examined by comparing which X chromosome the cells were using between different age groups and between neutrophils and T cells.
 
 In other words, they studied human hematopoiesis across age by analyzing purified blood cell lineages from the subjects.
 
 -----
 
-Modell/material
+## Study
-- 197 hematologically normal females
+- 1 97 hematologically normal females
-	- 23 new born
+	- 23 newborn
 	- 94 young adult (median 30)
 	- 80 eldery (over 75)
 - purified neutrofils
@@ -30,22 +30,22 @@ Modell/material
 
 ---
 
-### Figure
+### Cord blood neutrophils
-![[image-183.png|177x186]] 
+![[image-183.png|287x302]] 
-Notes
+<small>
-- This graph shows the distribution of X chromosome usage in 23 newborn females
+- Graph shows the distribution of X chromosome usage in 23 newborn
-- X-axis: the % of cells using the less common X chromosome.
+- X-axis: % of cells using the less common X chromosome.
-	- 50% means perfectly (50% maternal / 50% paternal)
+- Y-axis: number of individuals in each group.
-	- 0/100% means all cells use the same chromosome
+Conclusion: Newborns mostly show balanced use of the two X chromosomes
-- Y-axis: number of individuals in each group
+</small>
 
-Conclusion: 
+---
-- Newborns mostly show balanced use of the two X chromosomes.
 
-![[image-184.png|177x193]]
+### > 75 years neutrophils
-Notes
+
+![[image-184.png|261x285]]
+<small>
 - This graph shows the purified neutrofils from 80 elderly (y >= 75) females
 - X and Y axis is the same as in previous graph
-
+Conclusion: Elderly neutrophils frequently show strongly uneven X chromosome usage.
-Conclusion:
+</small> 
-- Elderly neutrophils frequently show strongly uneven X chromosome usage.