From 9b004519777719306138f02654866f889debc542 Mon Sep 17 00:00:00 2001 From: Johan Dahlin Date: Fri, 16 Jan 2026 14:54:04 +0100 Subject: [PATCH] vault backup: 2026-01-16 14:54:04 --- .../image-converter-image-alignments.json | 17 +-------- content/Vetenskaplig artikel/Intro.md | 35 ++++++++++++------- 2 files changed, 24 insertions(+), 28 deletions(-) diff --git a/content/.obsidian/plugins/image-converter/image-converter-image-alignments.json b/content/.obsidian/plugins/image-converter/image-converter-image-alignments.json index 6701737..9e26dfe 100644 --- a/content/.obsidian/plugins/image-converter/image-converter-image-alignments.json +++ b/content/.obsidian/plugins/image-converter/image-converter-image-alignments.json @@ -1,16 +1 @@ -{ - "Vetenskaplig artikel/Intro.md": { - "aca677ab589429f9db4b9295c7397939": { - "position": "center", - "width": "148px", - "height": "156px", - "wrap": false - }, - "d765982220ac8d6615dac423d5f86ecc": { - "position": "center", - "width": "145px", - "height": "158px", - "wrap": false - } - } -} \ No newline at end of file +{} \ No newline at end of file diff --git a/content/Vetenskaplig artikel/Intro.md b/content/Vetenskaplig artikel/Intro.md index 1103675..4f42c90 100644 --- a/content/Vetenskaplig artikel/Intro.md +++ b/content/Vetenskaplig artikel/Intro.md @@ -1,21 +1,32 @@ - The aim of the study was to investigate whether normal aging leads to blood cells being produced from fewer cell clones. This was examined by comparing which X chromosome the cells were using between different age groups and between neutrophils and T cells. - -In other words, they studied human hematopoiesis acros s age by analyzing purified blood cell lineages from the subjects. +--- +aliases: +--- --- 👋 +--- + + The aim of the study was to investigate whether normal aging leads to blood cells being produced from fewer cell clones. This was examined by comparing which X chromosome the cells were using between different age groups and between neutrophils and T cells. + +In other words, they studied human hematopoiesis acros s age by analyzing purified blood cell lineages from the subjects. + + ------- ## Study - 197 hematologically normal females - - 23 newborn - taken during delivery - - 94 young adult - age: 17-50 median 30 - - 80 eldery - age: 75-96 median 81 -- purified neutrofils -- purified T-cells + + +| | Sample size | Age | Median | +| ----------- | ----------- | ----- | ------ | +| Newborn | 23 | 0 | 0 | +| Young adult | 94 | 17-50 | 30 | +| Eldery | 80 | 75-96 | 81 | + + ---- ### Methods -1. Peripheral blood samples were collected -2. Neutrophils and T cells were isolated using cell separation techniques _(centrifugation followed by lineage-specific purification)_ -3. X-chromosome inactivation was analyzed using the HUMARA PCR assay _(PCR-based measurement of which X chromosome is active)_ -4. T cells were analyzed by PCR to check for clonal expansion _(T-cell receptor γ gene rearrangement analysis)_ \ No newline at end of file +- Peripheral blood samples were collected +- Neutrophils and T cells were isolated using cell separation techniques _(centrifugation followed by lineage-specific purification)_ +- X-chromosome inactivation was analyzed using the HUMARA PCR assay _(PCR-based measurement of which X chromosome is active)_ +- T cells were analyzed by PCR to check for clonal expansion _(T-cell receptor γ gene rearrangement analysis)_ \ No newline at end of file