vault backup: 2025-12-09 15:12:34

content/Biokemi/Gamla tentor/2025-02-01/4.md

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+---
+date: 2025-02-01
+tags:
+  - biokemi
+  - provfråga
+  - hemoglobin
+---
+
+**Uppgift**  
+A) Name two allosteric regulators of oxygen binding to hemoglobin.  
+B) Explain an outcome for each regulator.  
+(Max 100 words.) Please answer this question in English. (4p)
+
+**Answer**
+```spoiler-block
+
+a) O₂ and CO₂  
+b)  
+O₂:  
+Hemoglobin has four subunits that bind to O₂ through cooperativity, meaning that if one subunit binds to an O₂, the other subunits' affinity for O₂ will increase, leading to all subunits binding to O₂. When O₂ binds, the state goes from T-state (deoxy; tense) to R-state (oxy; relaxed).  
+
+CO₂:  
+When CO₂ binds to hemoglobin, the hemoglobin's affinity to oxygen decreases, leading to a stabilization of the T-state instead.  
+
+```
+Totalpoäng: 4