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Johan Dahlin
2025-12-09 15:12:34 +01:00
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---
date: 2024-12-20
tags:
- biokemi
- provfråga
- lipider
---
**Uppgift**
Beskriv hur triacylglycerol i fettceller bryts ner till fria fettsyror. (4p)
**Svar**
```spoiler-block
Adrenalin eller glukagon inducerar intracellulära reaktioner via 7TM, vilket omvandlar ATP till cAMP. cAMP aktiverar proteinkinas A, som i sin tur aktiverar perilipin. Perilipin omarrangerar TAG så att ATGL kan klyva den första fettsyran (TAG blir DAG). Proteinkinas A aktiverar HS lipas som spjälkar den andra fettsyran (DAG till MAG). MAG lipas spjälkar den tredje fettsyran, så att det bara blir kvar glycerol.
```
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