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content/Biokemi/Gamla tentor/2023-05-15/4.md
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content/Biokemi/Gamla tentor/2023-05-15/4.md
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---
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date: 2023-05-15
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tags:
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- biokemi
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- provfråga
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- hemoglobin
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---
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Nämn de allosteriska regulatorerna för hemoglobin och ange om de höjer eller sänker hemoglobinets syreaffinitet. (2p) Max 25 ord.
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**Svar**
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```spoiler-block
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CO₂: bildar kolsyra & karbamatjoner, sänker pH.
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H⁺: interagerar med sidokedjor, uppstår jonbindningar.
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2,3-BPG: binder subenheterna, förhindrar konformationsändring.
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Samtliga stabiliserar T-state, sänker affiniteten för syre.
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```
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