From 4a1370b7b4a3d56bdbcbf770e4c6442897e56917 Mon Sep 17 00:00:00 2001 From: Johan Dahlin Date: Wed, 17 Dec 2025 23:17:09 +0100 Subject: [PATCH] vault backup: 2025-12-17 23:17:09 --- content/.obsidian/workspace.json | 38 +++++++++---------- content/Biokemi/Metabolism/đŸ©ž Heme/Studera.md | 21 ++++++++++ 2 files changed, 39 insertions(+), 20 deletions(-) create mode 100644 content/Biokemi/Metabolism/đŸ©ž Heme/Studera.md diff --git a/content/.obsidian/workspace.json b/content/.obsidian/workspace.json index 75a71d2..c1baa61 100644 --- a/content/.obsidian/workspace.json +++ b/content/.obsidian/workspace.json @@ -11,15 +11,12 @@ "id": "c5854120d39261cd", "type": "leaf", "state": { - "type": "markdown", + "type": "pdf", "state": { - "file": "Biokemi/CellulĂ€ra processer/Utforska proteiner/LĂ€randemĂ„l.md", - "mode": "source", - "source": false, - "backlinks": false + "file": "Biokemi/Metabolism/đŸ©ž Heme/Slides.pdf" }, - "icon": "lucide-file", - "title": "LĂ€randemĂ„l" + "icon": "lucide-file-text", + "title": "Slides" } } ] @@ -54,8 +51,8 @@ "state": { "type": "search", "state": { - "query": "tag:#provfrĂ„ga IF2 ", - "matchingCase": true, + "query": "Hemolys", + "matchingCase": false, "explainSearch": false, "collapseAll": false, "extraContext": true, @@ -174,7 +171,8 @@ } ], "direction": "horizontal", - "width": 200 + "width": 200, + "collapsed": true }, "left-ribbon": { "hiddenItems": { @@ -190,6 +188,16 @@ }, "active": "c5854120d39261cd", "lastOpenFiles": [ + "Biokemi/Metabolism/đŸ©ž Heme/Studera.md", + "Biokemi/Gamla tentor/2024-01-27/33.md", + "Biokemi/Metabolism/PentosfosfatvĂ€gen/📚 Instuderingsuppgifter.md", + "Biokemi/Metabolism/đŸ©ž Heme/ProvfrĂ„gor.md", + "Biokemi/Gamla tentor/2024-01-27/2024-01-27-0096-APG.md", + "Biokemi/Gamla tentor/2024-01-27/2024-01-27-0096-APG.pdf", + "Biokemi/Gamla tentor/2024-01-27/30.md", + "Biokemi/Metabolism/đŸ©ž Heme/Slides.pdf", + "Biokemi/CellulĂ€ra processer/Utforska proteiner/Slides.pdf.pdf", + "Biokemi/CellulĂ€ra processer/Utforska proteiner/LĂ€randemĂ„l.md", "Biokemi/Plasmidlabb/Anteckningar I.md", "Biokemi/Behöver göra.md", "conflict-files-obsidian-git.md", @@ -220,16 +228,6 @@ "Biokemi/Gamla tentor/2024-08-01/13.md", "Biokemi/CellulĂ€ra processer/Translation/Stoff.md", "Biokemi/Metabolismseminarie/4. Syre i ETK.md", - "Biokemi/Metabolismseminarie/6. Glykogen.md", - "Biokemi/CellulĂ€ra processer/Transport över cellmembran/Stoff.md", - "Biokemi/Gamla tentor/2023-05-15/17.md", - "Biokemi/Gamla tentor/2022-01-29/32.md", - "Biokemi/Metabolism/🧂 Glykogen/Slides.pdf.pdf", - "Biokemi/Metabolism/🧂 Glykogen/Anteckingar.md", - "table-export-001.xlsx", - "table-export-001.csv", - "Biokemi/Regleringar.md", - "Biokemi/Makromolekyler/Nukleotider/InstuderingsfrĂ„gor.md", "attachments/Pasted image 20251129234842.png", "Untitled.canvas", "Biokemi/Metabolism/Diagram/Glycolysis_overview.svg", diff --git a/content/Biokemi/Metabolism/đŸ©ž Heme/Studera.md b/content/Biokemi/Metabolism/đŸ©ž Heme/Studera.md new file mode 100644 index 0000000..c98d9ff --- /dev/null +++ b/content/Biokemi/Metabolism/đŸ©ž Heme/Studera.md @@ -0,0 +1,21 @@ + +### 1. Hemesyntes (4p-frĂ„ga) + +- [x] **Substrat:** Veta att Succinyl-CoA + **glycin** startar processen. +- [x] **Enzym:** Kunna namnet **ALA-syntas** (ALAS). +- [ ] **JĂ€rnreglering:** FörstĂ„ att jĂ€rn styr **translationen** via **IRE** (pĂ„ mRNA) och **IRP** (protein). +- [ ] **Slutsteg:** Veta att **ferrokelatas** sĂ€tter in Fe2+ i porfyrinringen. + +### 2. Nedbrytning & Utsöndring (4p-frĂ„ga) + +- [x] **MjĂ€lten:** Heme bryts ner till **biliverdin** och sedan **okonjugerat bilirubin**. +- [x] **Transport:** Okonjugerat bilirubin binds till **albumin** i blodet (eftersom det Ă€r hydrofobt). +- [x] **Levern:** Bilirubin **konjugeras** med **glukuronsyra** för att bli vattenlösligt. +- [x] **Exkretion:** Utsöndras via **gallan** till tarmen och ut med avföring. + +### 3. Kliniska kopplingar & Diagnostik + +- [ ] **Ikterus (Gulsot):** FörstĂ„ skillnaden mellan pre-, hepatisk och posthepatisk orsak. +- [ ] **Hemolys:** Veta att detta ger förhöjt **okonjugerat** (indirekt) bilirubin. +- [ ] **Porfyri:** Veta att det beror pĂ„ enzymdefekter och kan ge buksmĂ€rtor (AIP) eller hudsymtom. +- [x] **Struktur:** Heme Ă€r en **protoporfyrinring** med en jĂ€rnjon i mitten. \ No newline at end of file